For some applications, the primary and secondary amines are often subjected to the Leuckart reaction.
2.
Due to the simplicity of the Leuckart reaction, it is the most popular synthetic route employed for the illicit manufacture of amphetamines.
3.
Researchers were able to synthesize tetrahydro-1, 4-benzodiazepin-5-ones with excellent yields and purities by utilizing the Leuckart Reaction.
4.
A notable example of the Leuckart reaction is its use in the synthesis of tetrahydro-1, 4 benzodiazepin-5-one, a molecule that is part of the benzodiazepine family.
5.
Formetorex is also an intermediate in the production of amphetamine by the " Leuckart reaction . " It is also commonly found as an impurity in clandestine labs where this synthesis method is used.
6.
Since the first preparation was reported in 1887, The most common route of both legal and illicit amphetamine synthesis employs a non-metal reduction known as the Leuckart reaction ( method 1 ).
7.
It was produced accidentally by Rudolf Leuckart in the reaction of benzaldehyde with formamide in a process now known as the Leuckart reaction, a general process in which reductive amination of aldehydes or ketones yields the corresponding amine.
8.
I'm thinking it is basically a Leuckart reaction to convert to-CH2-C (-NH2 )-CH3, which is a two step process of adding formamide and then getting rid of the " form " bit.
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